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JoVE Journal
Biology

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Xenopus laevis as a Model to Identify Translation Impairment
 

Xenopus laevis as a Model to Identify Translation Impairment

Article DOI: 10.3791/52724
September 27th, 2015

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Summary September 27th, 2015

Protein synthesis control occurs mainly at the translation initiation step, deficiencies in which are linked to diverse disorders. To better understand their etiology, we described here a protocol using Xenopus laevis oocytes assessing the translation of mos transcript in the presence of a mutant of translation initiation factor eIF4G1.

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