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Xenopus laevis as a Model to Identify Translation Impairment
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Xenopus laevis as a Model to Identify Translation Impairment

Article DOI: 10.3791/52724
September 27th, 2015 •
1, 1, 2, 2, 1, 2, 1, 1
1Team "Early Stages of Parkinson's Disease" of the Jean-Pierre Aubert Research Center, INSERM UMR-S1172, CHRU Lille, University of Lille 1 and Lille 2, 2Team "Signal Division Regulation", CNRS UMR 8576, University of Lille 1

Chapters

Summary
Automatic Translation
September 27th, 2015

Protein synthesis control occurs mainly at the translation initiation step, deficiencies in which are linked to diverse disorders. To better understand their etiology, we described here a protocol using Xenopus laevis oocytes assessing the translation of mos transcript in the presence of a mutant of translation initiation factor eIF4G1.

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