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Journal / Medicine / Induktion af accelereret åreforkalkning i Mus:…
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Induktion af accelereret åreforkalkning i Mus
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Induktion af accelereret åreforkalkning i Mus: Den "Wire-Skade" Model

Article DOI: 10.3791/54571-v • 05:35 min • August 25th, 2020
August 25th, 2020 •
1, 1, 1, 1,2
1Institute for Molecular Cardiovascular Research, RWTH Aachen University, 2Human Genetic Laboratory, University of Medicine and Pharmacy

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Denne undersøgelse beskriver en invasiv procedure for induktion af accelereret åreforkalkning hos mus. I forhold til andre metoder, der anvender elektrisk- eller kryo-induceret skade, mekanisk-induceret skade efterligner den menneskelige tilstand af restenosis efter revaskularisering behandlinger og er ideel til undersøgelse af de molekylære involverede mekanismer.

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Medicin Åreforkalkning musemodel neointima formation stabil aterosklerotisk plaque
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