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May 21, 2017
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Uncontrolled hemorrhage, an important cause of mortality among trauma patients, can be modeled using a standard liver laceration in a murine model. This model results in consistent blood loss, survival, and allows for testing hemostatic agents. This article provides the step-by-step process to perform this valuable model.
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Cite this Article
Dyer, M., Haldeman, S., Gutierrez, A., Kohut, L., Sen Gupta, A., Neal, M. D. Uncontrolled Hemorrhagic Shock Modeled via Liver Laceration in Mice with Real Time Hemodynamic Monitoring. J. Vis. Exp. (123), e55554, doi:10.3791/55554 (2017).
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