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Fixed Volume or Fixed Pressure: A Murine Model of Hemorrhagic Shock
JoVE Journal
Medicine
This content is Free Access.
JoVE Journal Medicine
Fixed Volume or Fixed Pressure: A Murine Model of Hemorrhagic Shock
DOI:

16:31 min

June 06, 2011

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Chapters

  • 00:05Title
  • 01:31Setup
  • 05:38Surgical and Experimental Procedures
  • 11:11Hemorrhagic Shock and Resuscitation
  • 13:49Representative Results
  • 16:00Conclusion

Summary

Automatic Translation

The Hemorrhagic Shock model has been a reliable and reproducible resource facilitating the identification and understanding of signaling cascades associated with inflammation and end-organ damage after trauma. This article provides a step-by-step description of surgical and mechanical aspects associated with the Hemorrhagic Shock experimental procedure in mice.

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