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JoVE Journal

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Fixed Volume or Fixed Pressure

Fixed Volume or Fixed Pressure: A Murine Model of Hemorrhagic Shock

Article DOI: 10.3791/2068
June 6th, 2011


Summary June 6th, 2011

The Hemorrhagic Shock model has been a reliable and reproducible resource facilitating the identification and understanding of signaling cascades associated with inflammation and end-organ damage after trauma. This article provides a step-by-step description of surgical and mechanical aspects associated with the Hemorrhagic Shock experimental procedure in mice.

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