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通过实时血液动力学监测在小鼠中通过肝脏浸润建立的不受控制的出血性休克
JoVE Journal
Medicine
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JoVE Journal
Medicine
Uncontrolled Hemorrhagic Shock Modeled via Liver Laceration in Mice with Real Time Hemodynamic Monitoring
Please note that all translations are automatically generated.
Click here for the English version.
通过实时血液动力学监测在小鼠中通过肝脏浸润建立的不受控制的出血性休克
DOI:
10.3791/55554-v
•
06:11 min
•
May 21, 2017
•
Mitchell Dyer
,
Shannon Haldeman
,
Andres Gutierrez
,
Lauryn Kohut
,
Anirban Sen Gupta
,
Matthew D. Neal
1
Department of Surgery
,
University of Pittsburgh
,
2
Department of Biomedical Engineering
,
Case Western Reserve University
Chapters
00:05
Title
00:47
Catheter Placement
02:34
Liver Laceration
03:42
Results: Representative Liver Laceration Analyses
05:04
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
不可控的出血是创伤患者死亡的重要原因,可以使用鼠模型中的标准肝脏撕裂进行建模。该模型导致失血,存活的一致性,并允许测试止血剂。本文提供了执行此有价值模型的分步过程。
Tags
Uncontrolled Hemorrhage
Hemorrhagic Shock
Resuscitation
Hemostatic Drugs
Molecular Mechanisms
Liver Laceration
Murine Model
Real-time Hemodynamic Monitoring
Femoral Artery Catheterization
Laparotomy
Blood Pressure
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