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Neuroscience

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JoVE Journal Neuroscience
Modellering Hurtig-scanning cyklisk voltammetri data fra elektrostimulerede data om dopaminneurotransmission ved hjælp af QNsim1.0
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Modellering Hurtig-scanning cyklisk voltammetri data fra elektrostimulerede data om dopaminneurotransmission ved hjælp af QNsim1.0

Article DOI: 10.3791/55595-v • 07:41 min • June 5th, 2017
June 5th, 2017 •
1,2,3, 2, 2,4, 1,2,3
1Center for Neuroscience, University of Pittsburgh, 2Department of Physical Medicine & Rehabilitation, University of Pittsburgh, School of Medicine, 3Safar Center for Resuscitation Research, University of Pittsburgh, 4Department of Biological Sciences, Mellon College of Science, Carnegie Mellon University

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Hurtig-scanning cyklisk voltammetri kan overvåge in vivo dopamin neurotransmission i forbindelse med stoffer, sygdom og andre eksperimentelle manipulationer. Dette arbejde beskriver implementeringen af ​​QNsim1.0, en software til modellering af elektrisk stimulerede dopaminresponser ifølge den kvantitative neurobiologiske model for at kvantificere estimater for dopaminfrigivelse og genoptagelsesdynamik.

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Neurovidenskab udgave 124 dopamin hurtigscanning cyklisk voltammetri synaptisk transmission psykostimulerende midler methylphenidat kvantitativ neurobiologisk model
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