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JoVE Journal Cancer Research
Inductie en diagnose van tumoren in
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Inductie en diagnose van tumoren in

Article DOI: 10.3791/55901-v • 08:14 min • July 25th, 2017
July 25th, 2017 •
1,2, 1
1Structural Biology Center, National Institute of Genetics and Department of Genetics, School of Life Science, SOKENDAI, 2Graduate School of Media and Governance, Keio University

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Mozaïek kloon analyse in Drosophila imaginal disc epithelia is een krachtig model systeem om de genetische en cellulaire mechanismen van tumorigenese te bestuderen. Hier beschrijven we een protocol om tumoren te induceren in Drosophila- vleugel-imaginale schijven met behulp van het GAL4-UAS-systeem, en introduceert een diagnose-methode om de tumorfenotypen te classificeren.

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Cancer Biology Drosophila Imaginale schijf Tumorigenese Neoplasia Dysplasie Tumor suppressor gen GAL4-UAS RNAi
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