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JoVE Journal
Immunology and Infection

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Intratracheal Inoculation of Fischer 344 Rats with Francisella tularensis
 

Intratracheal Inoculation of Fischer 344 Rats with Francisella tularensis

Article doi: 10.3791/56123
September 30th, 2017

Summary September 30th, 2017

This protocol describes intratracheal inoculations of Fischer 344 rats with Francisella tularensis. This procedure mimics pulmonary exposure of humans to this potential biothreat agent and can be used to test vaccine and therapeutic efficacy against pulmonary tularemia.

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