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In Vitro Enzym måling til Test farmakologiske anstandsdame lydhørhed i Fabry og Pompe sygdom
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In Vitro Enzym måling til Test farmakologiske anstandsdame lydhørhed i Fabry og Pompe sygdom

Article DOI: 10.3791/56550-v • 10:16 min • December 20th, 2017
December 20th, 2017 •
1, 1, 1, 2, 2, 1,3
1Albrecht-Kossel-Institute, University Rostock Medical Center, 2Department of Biology, University Federico II, 3Centogene AG

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Der er et krav til præ-klinisk test for en ny klasse af "sjældne" lægemidler kaldet farmakologiske chaperoner reproducerbar, hurtig og effektiv. Vi udviklet en enkel, meget standardiserede og alsidig celle kultur-baseret analyse til skærmen for støtteberettigede patienter samt roman farmakologiske anstandsdame lægemidler.

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Medicin spørgsmål 130 lysosomale opbevaring lidelse fænotype glycosidase lille molekyle narkotika prækliniske test individualiseret terapi
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