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En kinetisk fluorescens-baserede Ca2 + mobilisering Assay at identificere G Protein-koblet Receptor agonister og antagonister allosteriske modulatorer
 
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En kinetisk fluorescens-baserede Ca2 + mobilisering Assay at identificere G Protein-koblet Receptor agonister og antagonister allosteriske modulatorer

Article DOI: 10.3791/56780
February 20th, 2018

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Summary February 20th, 2018

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Den beskrevne cellulære assay er designet til identifikation af CXC chemokine receptor 4 (CXCR4)-interagerende agenter, der hæmmer eller stimulere enten konkurrencedygtige eller allosterically, den intracellulære Ca2 + release initieret af CXCR4 aktivering.

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