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JoVE Journal
Genetics

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Manipulation of Ploidy in Caenorhabditis elegans
 

Manipulation of Ploidy in Caenorhabditis elegans

Article DOI: 10.3791/57296
March 15th, 2018

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Summary March 15th, 2018

This method allows for the generation of tetraploid and triploid Caenorhabditis nematodes from any diploid strain. Polyploid strains generated by this method have been used to study chromosome interactions in meiotic prophase, and this method is useful for examining important basic questions in cell, developmental, evolutionary, and cancer biology.

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