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Un nuovo metodo semplice per la misurazione di lipofilia (logP) utilizzando 19F NMR spettroscopia
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Un nuovo metodo semplice per la misurazione di lipofilia (logP) utilizzando 19F NMR spettroscopia

Article DOI: 10.3791/58567-v • 09:32 min • January 30th, 2019
January 30th, 2019 •
1, 1, 1, 1, 2, 1
1Chemistry, University of Southampton, 2Medicinal Chemistry, Oncology, IMED Biotech Unit, AstraZeneca

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Un romanzo e una semplice variazione del metodo del dibattimento in pallone è stato sviluppato per la misura accurata lipofilia di composti fluorurati dalla spettroscopia NMR F 19.

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Chimica numero 143 liposolubilità organofluoruro 19F NMR fluorurazione fluorurati alkanols carboidrati
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