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Journal / Developmental Biology / Un modello 3D in vitro e una pipeline…
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Developmental Biology

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JoVE Journal Developmental Biology
Un modello 3D in vitro e una pipeline computazionale per quantificare il potenziale vasculogenico dei progenitori endoteliali derivati da iPSC
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Un modello 3D in vitro e una pipeline computazionale per quantificare il potenziale vasculogenico dei progenitori endoteliali derivati da iPSC

Article DOI: 10.3791/59342-v • 06:36 min • May 13th, 2019
May 13th, 2019 •
1, 1
1Department of Biomedical Engineering, University of Texas at Austin

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I progenitori endoteliali derivati da cellule staminali pluripotenti indotte (iPSC-EP) hanno il potenziale di rivoluzionare i trattamenti delle malattie cardiovascolari e di consentire la creazione di modelli di malattie cardiovascolari più fedeli. Qui, vengono descritti l'incapsulamento di iPS-EP in microambienti tridimensionali di collagene (3D) e un'analisi quantitativa del potenziale vasculogenico di queste cellule.

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Biologia dello sviluppo numero 147 cellule staminali progenitore endoteliale vasculogenesi matrice extracellulare collagene analisi computazionale reti di navi
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