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Glomeruläres Outgrowth als Ex-Vivo-Assay zur Analyse von Pfaden, die an der Parietalepithel Cell Activation beteiligt sind

Article DOI: 10.3791/60324-v • 06:39 min • August 19th, 2020
August 19th, 2020 •
1, 1, 1, 1,2, 3, 4, 1
1Radboud Institute for Molecular Life Sciences, Department of Pathology, Radboud University Medical Center, 2Radboud Institute for Molecular Life Sciences, Amalia Children's Hospital, Department of Paediatric Nephrology, Radboud University Medical Center, 3Radboud Institute for Health Sciences, Department of Nephrology, Radboud University Medical Center, 4Radboud Institute for Molecular Life Sciences, Department of Nephrology, Radboud University Medical Center

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Dieser Artikel beschreibt eine Methode zur Kultivierung und Analyse glomerulären parietalen Epithelzellauswüchsen von verkapselten Glomeruli, die aus der Mausniere isoliert sind. Diese Methode kann verwendet werden, um Wege zu untersuchen, die an der Proliferation und Migration von parietalen Epithelzellen beteiligt sind.

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Biologie Ausgabe 162 Niere Ex-vivo-Assay glomeruläres Auswuchs Glomerulosklerose parietale Epithelzellen Proliferation
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