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JoVE Journal
Medicine

This content is Open Access.

Investigating Intestinal Barrier Breakdown in Living Organoids
 

Investigating Intestinal Barrier Breakdown in Living Organoids

Article doi: 10.3791/60546
March 26th, 2020

Summary March 26th, 2020

Here we describe a technique to quantify the barrier integrity of small intestinal organoids. The fact that the method is based on living organoids enables the sequential investigation of different barrier integrity modulating substances or combinations thereof in a time-resolved manner.

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