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Påvisning af lungetumorprogression hos mus ved ultralydsscanning
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Påvisning af lungetumorprogression hos mus ved ultralydsscanning

Article DOI: 10.3791/60565-v • 04:43 min • February 27th, 2020
February 27th, 2020 •
1,2, 1, 1, 1,3, 1, 1,4
1Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, 2Division of Experimental Medicine, Faculty of Medicine, McGill University, 3Department of Cancer Immunology, Chair of Medical Biotechnology, Poznan University of Medical Sciences, 4Gerald Bronfman Department of Oncology, Faculty of Medicine, McGill University

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Denne protokol beskriver de skridt, der er taget for at fremkalde KRAS lungetumorer i mus samt kvantificering af dannede tumorer ved ultralydsscanning. Små tumorer visualiseres i tidlige tidspunkter som B-linjer. På senere tidspunkter, relative tumor volumen målinger opnås ved måleværktøjet i ultralyd software.

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Cancer Research lungekræft LSL-KRAS G12D musemodel ultralydsscanning 2D volumenkvantificering tumordannelse B-tilstand
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