A subscription to JoVE is required to view this content. Sign in or start your free trial.
1Department of Clinical Neurophysiology,Aarhus University Hospital, 2UCL Queen Square Institute of Neurology, Queen Square House, 3Departments of Neurology and Neurosurgery, Inselspital, Bern University Hospital,University of Bern, 4MRC Centre for Neuromuscular Diseases, UCL Institute of Neurology,The National Hospital for Neurology and Neurosurgery
Chapters
- 00:04Introduction
- 01:25Preparation of the Subject
- 03:09Recording of the MVRCs (Muscle Velocity Recovery Cycles)
- 05:23MVRC Analyses
- 07:29Results: Healthy Controls and Patients
- 08:01Conclusion
Presented here is a protocol for the recording of muscle velocity recovery cycles (MVRCs), a new method of examining muscle membrane properties. MVRCs enable in vivo assessment of muscle membrane potential and alterations in muscle ion channel function in relation to pathology, and it enables the demonstration of muscle depolarization in neurogenic muscles.
