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JoVE Journal
Neuroscience

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Paired Patch Clamp Recordings from Motor-neuron and Target Skeletal Muscle in Zebrafish
 

Paired Patch Clamp Recordings from Motor-neuron and Target Skeletal Muscle in Zebrafish

Article DOI: 10.3791/2351
November 20th, 2010

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Summary November 20th, 2010

Larval zebrafish represent the first vertebrate model system to allow simultaneous patch clamp recording from a spinal motor-neuron and target skeletal muscle. This video demonstrates the microscopic methods used to identify a segmental CaP motor-neuron and target muscle cells as well as the methodologies for recording from each cell type.

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