JoVE Journal
Biology
Biology
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生成用于发育和疾病建模应用的 hiPSC 衍生肠道类器官
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Article
DOI:
10.3791/61199-v
•
06:34 min
•
March 8th, 2024
生成用于发育和疾病建模应用的 hiPSC 衍生肠道类器官
March 8th, 2024
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Paulina M. Durczak*1, Kathryn L. Fair*1, Nicholas Jinks1, Sara Cuevas Ocaña1, Carlos B. Sainz Zuñiga1, Nicholas R.F. Hannan1
1Biodiscovery Institute, Translational Medical Sciences, School of Medicine, University of Nottingham
* These authors contributed equally
Chapters
Summary
Please note that all translations are automatically generated.
Click here for the English version.
该协议允许将人类多能细胞分化为肠道类器官。该协议通过将细胞分化为确定的内胚层,后肠内胚层和肠上皮细胞群来模拟正常的人类发育。这使得该协议适用于研究肠道发育和疾病建模应用。