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JoVE Journal
Biology

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生成用于发育和疾病建模应用的 hiPSC 衍生肠道类器官
 
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生成用于发育和疾病建模应用的 hiPSC 衍生肠道类器官

Article DOI: 10.3791/61199-v 06:34 min March 8th, 2024
March 8th, 2024

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Summary

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该协议允许将人类多能细胞分化为肠道类器官。该协议通过将细胞分化为确定的内胚层,后肠内胚层和肠上皮细胞群来模拟正常的人类发育。这使得该协议适用于研究肠道发育和疾病建模应用。

Tags

本月JoVE第205期,肠道类器官,后肠,干细胞,内胚层,炎症,疾病建模
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