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Journal / Bioengineering / The Preparation of Chicken Ex Ovo Embryos and…
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Bioengineering

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JoVE Journal Bioengineering
The Preparation of Chicken Ex Ovo Embryos and Chorioallantoic Membrane Vessels as In Vivo Model for Contrast-Enhanced Ultrasound Imaging and Microbubble-Mediated Drug Delivery Studies
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The Preparation of Chicken Ex Ovo Embryos and Chorioallantoic Membrane Vessels as In Vivo Model for Contrast-Enhanced Ultrasound Imaging and Microbubble-Mediated Drug Delivery Studies

Article DOI: 10.3791/62076-v • 09:53 min • February 9th, 2021
February 9th, 2021 •
1, 1, 1,2, 1,2, 1
1Department of Biomedical Engineering, Thoraxcenter, Erasmus MC University Medical Center Rotterdam, 2Laboratory of Acoustical Wavefield Imaging, Faculty of Applied Sciences, Delft University of Technology

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Summary
Automatic Translation

This protocol describes three methods on how to obtain and use 5 to 8-day old chicken embryos and their chorioallantoic membrane (CAM) as an in vivo model to study contrast-enhanced ultrasound imaging and microbubble-mediated drug delivery.

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Chicken Embryos In Vivo Model Contrast-enhanced Ultrasound Imaging Microbubble-mediated Drug Delivery Preparation Incubation Egg Shell Lab Tools Ultrasound And Vascular Research Blood Flow Imaging Drug Delivery Ultrasound Contrast Agents Transducers Egg Holder Indentation Eggshell Removal Air Sac Syringe Needle
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