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Caracterización funcional de variantes de RYR1 humanas expresadas endógenamente
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Caracterización funcional de variantes de RYR1 humanas expresadas endógenamente

Article DOI: 10.3791/62196-v • 07:59 min • June 9th, 2021
June 9th, 2021 •
1,2, 3, 1,2
1Department of Biomedicine, Basel University Hospital, 2Department of Life Sciences, University of Ferrara, 3Department of Anesthesia, Basel University Hospital

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Aquí se describen los métodos utilizados para estudiar el efecto funcional de las mutaciones RYR1 expresadas endógenamente en los linfocitos B humanos inmortalizados por el virus de Epstein Barr y las células satélite derivadas de biopsia muscular diferenciadas en miotubos.

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Medicina Número 172 RYR1 mutaciones caracterización funcional expresión endógena miotubos Linfoblastos del VEB calcio dosis respuesta
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