Waiting
Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Biochemistry / NMR-baseret fragmentscreening i en minimumsprøve, …
JoVE Journal
Biochemistry

This content is Open Access.

JoVE Journal Biochemistry
NMR-baseret fragmentscreening i en minimumsprøve, men maksimal automatiseringstilstand
Preparation of High-Temperature Sample Grids for Cryo-EM
Journal (Biochemistry)
Preparation of High-Temperature Sample Grids for Cryo-EM
A Colorimetric Assay of Citrate Synthase Activity in Drosophila Melanogaster
Journal (Biochemistry)
A Colorimetric Assay of Citrate Synthase Activity in Drosophila Melanogaster
 
Click here for the English version

NMR-baseret fragmentscreening i en minimumsprøve, men maksimal automatiseringstilstand

Article DOI: 10.3791/62262-v • 09:19 min • June 4th, 2021
June 4th, 2021 •
*1, *1, 1,2, 1, 1, 1,2
1Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ), Johann Wolfgang Goethe-University Frankfurt, 2German Cancer Consortium (DKTK) and DKFZ
* These authors contributed equally

Chapters

Summary
Automatic Translation

Please note that all translations are automatically generated.

Click here for the English version.

Fragmentbaseret screening ved NMR er en robust metode til hurtigt at identificere små molekylebindere til biomakromolekyler (DNA, RNA eller proteiner). Protokoller, der beskriver automatiseringsbaseret prøveforberedelse, NMR-eksperimenter og erhvervelsesbetingelser og analysearbejdsgange, præsenteres. Teknikken giver mulighed for optimal udnyttelse af både 1H og 19F NMR-aktive kerner til detektion.

Tags

Denne måned i JoVE udgave 172 Fragmentbaseret screening Automatisering Løsning NMR-spektroskopi Dataindsamling og analyse Screeningsplatform Fragmentbibliotek
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter