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Journal / Biochemistry / Generere selvmontering av humane hjerteorganoider …
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JoVE Journal Biochemistry
Generere selvmontering av humane hjerteorganoider avledet fra pluripotente stamceller
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Generere selvmontering av humane hjerteorganoider avledet fra pluripotente stamceller

Article DOI: 10.3791/63097-v • 08:56 min • September 15th, 2021
September 15th, 2021 •
1,2, 1,2, 1,2, 1,2, 1,2
1Institute for Quantitative Health Science and Engineering, Division of Developmental and Stem Cell Biology, Michigan State University, 2Department of Biomedical Engineering, College of Engineering, Michigan State University

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Her beskriver vi en protokoll for å skape utviklingsrelevante humane hjerteorganoider (hHOer) effektivt ved hjelp av menneskelige pluripotente stamceller av selvorganisering. Protokollen er avhengig av sekvensiell aktivering av utviklingssignaler og produserer svært komplekse, funksjonelt relevante menneskelige hjertevev.

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