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JoVE Journal Biochemistry
Generering af selvopsamlende menneskehjerteorganoider afledt af pluripotente stamceller
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Generering af selvopsamlende menneskehjerteorganoider afledt af pluripotente stamceller

Article DOI: 10.3791/63097-v • 08:56 min • September 15th, 2021
September 15th, 2021 •
1,2, 1,2, 1,2, 1,2, 1,2
1Institute for Quantitative Health Science and Engineering, Division of Developmental and Stem Cell Biology, Michigan State University, 2Department of Biomedical Engineering, College of Engineering, Michigan State University

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Her beskriver vi en protokol til at skabe udviklingsrelevante menneskelige hjerteorganoider (hHOs) effektivt ved hjælp af menneskelige pluripotente stamceller fra selvorganisering. Protokollen er afhængig af sekventiel aktivering af udviklingsmæssige signaler og producerer meget komplekse, funktionelt relevante menneskelige hjertevæv.

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Biokemi udgave 175
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