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JoVE Journal Neuroscience
Fuldcirkel cauterization af limbal vaskulær plexus til kirurgisk induceret glaukom hos gnavere
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Fuldcirkel cauterization af limbal vaskulær plexus til kirurgisk induceret glaukom hos gnavere

Article DOI: 10.3791/63442-v • 10:10 min • February 15th, 2022
February 15th, 2022 •
1, 1, 1, 1, 1, 1
1Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro

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Målet med denne protokol er at karakterisere en ny model af glaukomatøs neurodegeneration baseret på 360 ° termisk cauterization af limbal vaskulær plexus, hvilket inducerer subakut okulær hypertension.

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fuldcirkel cauterization limbal vaskulær plexus kirurgisk induceret glaukom gnavere glaukom blindhed okulære lidelser optisk nerveskade retinal ganglioncelledegeneration visuel dysfunktion intraokulært tryk okulær hypertension modeller genetiske tilgange eksperimentelle tilgange kirurgisk invasivitet funktionel vurdering retinal skade lav temperatur cauterization vandig humor dræning noninvasiv metode reproducerbar okulær hypertension progressiv RGC degeneration Optisk nervedegeneration Postoperativ klinisk restitutionsrate Elektrofysiologiske undersøgelser Adfærdsstudier
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