Journal
/
Medicine
/
Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control
JoVE Journal
Medicine
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Medicine
Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control

Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control

DOI:
10.3791/63921-v

•

05:41 min

•

December 16, 2022

•

, , ,
1Department of Life Science,Fu Jen Catholic University, 2Department of Medicine,MacKay Medical College, 3Department of Emergency Medicine,MacKay Memorial Hospital, 4Graduate Institute of Injury Prevention and Control,Taipei Medical University, 5MacKay Junior College of Medicine, Nursing, and Management, 6Division of Cardiology, Department of Internal Medicine,Taitung Mackay Memorial Hospital, 7Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine,MacKay Memorial Hospital

Chapters

  • 00:05Introduction
  • 00:30Preparation Before Surgery
  • 01:37Left Anterior Descending Coronary Artery (LAD Ligation)
  • 04:33Results: Validation of LAD Ligation and Quantification of Infarct Size and Area at Risk
  • 05:18Conclusion

Summary

Automatic Translation

Automatic Translation

Herein, we present a protocol focusing on the quality control of the left anterior descending coronary artery ligation by technically modifying the traditional procedure in rats for acute myocardial ischemia-reperfusion research.

Tags

Ischemia-reperfusionLeft Anterior Descending Coronary ArteryLigationRat ModelThoracotomySurgical ProcedureCotton BallsHolding HooksLigation LoopSnare Loop ControllerAnesthesiaEndotracheal IntubationRib ResectionSurgical WindowPericardium Exposure

Article

Embed

ADD TO PLAYLIST

Usage Statistics

Related Videos

Coronary Artery Ligation and Intramyocardial Injection in a Murine Model of Infarction

Modified Technique for Coronary Artery Ligation in Mice

A Murine Model of Myocardial Ischemia-reperfusion Injury through Ligation of the Left Anterior Descending Artery

Permanent Ligation of the Left Anterior Descending Coronary Artery in Mice: A Model of Post-myocardial Infarction Remodelling and Heart Failure

Murine Model of Intestinal Ischemia-reperfusion Injury

Murine Left Anterior Descending (LAD) Coronary Artery Ligation: An Improved and Simplified Model for Myocardial Infarction

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery (ALCAPA)

Isometric Contractility Measurement of the Mouse Mesenteric Artery Using Wire Myography

Two-vessel Occlusion Mouse Model of Cerebral Ischemia-reperfusion

Evaluation of Coronary Flow Reserve After Myocardial Ischemia Reperfusion in Rats

Read Article