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Journal / Biology / Ontcijferen van 3D-chromatineorganisatie met hoge …
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Ontcijferen van 3D-chromatineorganisatie met hoge resolutie via Capture Hi-C
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Ontcijferen van 3D-chromatineorganisatie met hoge resolutie via Capture Hi-C

Article DOI: 10.3791/64166-v • 09:32 min • October 14th, 2022
October 14th, 2022 •
1, 1, 2, 1, 3, 4, 1, 1,5
1EMBL: European Molecular Biology Laboratory, 2Institut Curie, 3Agilent Technologies, 4Genmab BV, 5Collège de France

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Dit protocol beschrijft de Capture Hi-C-methode die wordt gebruikt om de 3D-organisatie van megagebaseerde gerichte genomische regio's met hoge resolutie te karakteriseren, inclusief grenzen van topologisch associërende domeinen (TAD's) en chromatine-interacties op lange afstand tussen regulerende en andere DNA-sequentie-elementen.

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