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Mikrofluidikassisterad selektiv depolarisering av axonala mitokondrier
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Mikrofluidikassisterad selektiv depolarisering av axonala mitokondrier

Article DOI: 10.3791/64196-v • 06:55 min • August 4th, 2022
August 4th, 2022 •
*1,2, *1,2, 2,3,4
1TUM Medical Graduate Center, Technical University of Munich, 2Max Planck Institute of Neurobiology, 3TUM School of Medicine, Institute of Neuronal Cell Biology, Technical University of Munich, 4Munich Cluster for Systems Neurology
* These authors contributed equally

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Detta protokoll beskriver sådd och färgning av neuronala mitokondrier i mikrofluidiska kamrar. Den fluidiska tryckgradienten i dessa kamrar möjliggör selektiv behandling av mitokondrier i axoner för att analysera deras egenskaper som svar på farmakologiska utmaningar utan att påverka cellkroppsfacket.

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Neurovetenskap nummer 186 Axon mitokondrier mikrofluidik neurodegeneration
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