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JoVE Journal Neuroscience
Organotypiske kulturer av voksen human cortex som en ex vivo-modell for human stamcelletransplantasjon og validering
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Organotypiske kulturer av voksen human cortex som en ex vivo-modell for human stamcelletransplantasjon og validering

Article DOI: 10.3791/64234-v • 07:16 min • December 9th, 2022
December 9th, 2022 •
1, 1, 1, 2, 1
1Laboratory of Stem Cells and Restorative Neurology, Lund Stem Cell Center, Lund University, 2Lund Stem Cell Center, Lund University

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Denne protokollen beskriver langsiktige organotypiske kulturer av voksen human cortex kombinert med ex vivo intrakortikal transplantasjon av induserte pluripotente stamcelleavledede kortikale progenitorer, som presenterer en ny metodikk for ytterligere å teste stamcellebaserte terapier for humane nevrodegenerative lidelser.

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