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Bioengineering

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JoVE Journal Bioengineering
Isolering av neste generasjons genterapivektorer gjennom engineering, strekkoding og screening av adeno-associated virus (AAV) kapsidvarianter
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Isolering av neste generasjons genterapivektorer gjennom engineering, strekkoding og screening av adeno-associated virus (AAV) kapsidvarianter

Article DOI: 10.3791/64389-v • 09:20 min • October 18th, 2022
October 18th, 2022 •
1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2,3,4,5
1Department of Infectious Diseases/Virology, Section Viral Vector Technologies, Medical Faculty, University of Heidelberg, 2BioQuant Center, BQ0030, University of Heidelberg, 3Cluster of Excellence CellNetworks, 4German Center for Infection Research (DZIF), 5German Center for Cardiovascular Research (DZHK)

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AAV peptid display bibliotek generering og påfølgende validering gjennom strekkoding av kandidater med nye egenskaper for etablering av neste generasjons AAVs.

Tags

Bioteknologi utgave 188 AAV AAV-bibliotek kapsidteknikk genterapi high-throughput screening NGS strekkodebibliotek
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