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Journal / Bioengineering / Isolatie van gentherapievectoren van de volgende…
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JoVE Journal Bioengineering
Isolatie van gentherapievectoren van de volgende generatie door middel van engineering, barcoding en screening van adeno-geassocieerde virus (AAV) capsid-varianten
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Isolatie van gentherapievectoren van de volgende generatie door middel van engineering, barcoding en screening van adeno-geassocieerde virus (AAV) capsid-varianten

Article DOI: 10.3791/64389-v • 09:20 min • October 18th, 2022
October 18th, 2022 •
1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2,3,4,5
1Department of Infectious Diseases/Virology, Section Viral Vector Technologies, Medical Faculty, University of Heidelberg, 2BioQuant Center, BQ0030, University of Heidelberg, 3Cluster of Excellence CellNetworks, 4German Center for Infection Research (DZIF), 5German Center for Cardiovascular Research (DZHK)

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AAV-peptideweergavebibliotheek generatie en daaropvolgende validatie door de barcodering van kandidaten met nieuwe eigenschappen voor het maken van AAV's van de volgende generatie.

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Bioengineering AAV AAV-bibliotheken capsid engineering gentherapie high-throughput screening NGS bibliotheken met streepjescode
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