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Journal / Medicine / Tavşanda travma sonrası osteoartrit oluşturmak…
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Tavşanda travma sonrası osteoartrit oluşturmak için tekrarlanabilir bir kıkırdak etki modeli
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Tavşanda travma sonrası osteoartrit oluşturmak için tekrarlanabilir bir kıkırdak etki modeli

Article DOI: 10.3791/64450-v • 08:42 min • November 21st, 2023
November 21st, 2023 •
*1,2,3, *3,4,6, 1, 1,3, 1,3, 2,3, 1,2,3, 5, 2,3,6, 1,3
1Department of Anatomy, Cell Biology and Physiology, Indiana University School of Medicine, 2Department of Orthopaedic Surgery, Indiana University School of Medicine, 3Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, 4School of Mechanical Engineering, Purdue University, 5Large Animal Resource Center, Indiana University School of Medicine, 6Department of Mechanical and Energy Engineering, Indiana University-Purdue University Indianapolis
* These authors contributed equally

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Tavşanlarda açık medial femoral kondil etki modeli, travma sonrası osteoartrit (PTOA) ve PTOA ilerlemesini azaltmak için yeni terapötik stratejiler üzerinde çalışmak için güvenilirdir. Bu protokol, bir çarpma kafasına sahip taşıyıcı tabanlı bir düşme kulesi kullanılarak tavşanlarda posterior medial femoral kondilin izole bir kıkırdak defektini oluşturur.

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