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JoVE Journal Cancer Research
Test af kræftimmunotermiske lægemidler i en humaniseret musemodel, der bærer humane tumorer
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Test af kræftimmunotermiske lægemidler i en humaniseret musemodel, der bærer humane tumorer

Article DOI: 10.3791/64606-v • 15:24 min • December 16th, 2022
December 16th, 2022 •
*1, *1, 1, 1, 2, 2, 3, 1, 2, 1
1Department of Immunology and Microbiology, School of Medicine, University of Colorado Denver Anschutz Medical Campus, 2Division of Oncology, School of Medicine, University of Colorado Denver Anschutz Medical Campus, 3Department of Medical Oncology, Catalan Institute of Oncology (ICO-L'Hospitalet)
* These authors contributed equally

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Denne protokol skitserer dannelsen af humane immunsystemmus (HIS) til immuno-onkologiske undersøgelser. Instruktioner og overvejelser i brugen af denne model til test af humane immunotermiske lægemidler på humane tumorer implanteret i denne model præsenteres med vægt på karakterisering af immunsystemets respons på tumoren.

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Kræftforskning nr. 190
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