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Proteine in singole cellule con gocciolina indirizzabile Microarrays di conteggio

Article DOI: 10.3791/56110-v • 12:25 min • July 6th, 2018
July 6th, 2018 •
*1, *1, 1, 1
1Institute of Chemical Biology, Department of Chemistry, Imperial College London
* These authors contributed equally

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Qui presentiamo indirizzabile gocciolina microarrays (ADMs), un metodo di matrice basata gocciolina in grado di determinare l'abbondanza assoluta della proteina in cellule singole. Dimostriamo la capacità di ADMs per caratterizzare l'eterogeneità nell'espressione della proteina oncosoppressore p53 in una linea cellulare di cancro umano.

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Ricerca sul cancro problema 137 gocciolina microfluidica analisi della proteina unicellulare eterogeneità microfluidica goccioline quantificazione assoluta p53 dimensioni della cella
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