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JoVE Journal
Immunology and Infection

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腹腔葡萄糖耐受试验、肺功能测定和肺固定研究肥胖和代谢障碍对肺部结局的影响
 
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腹腔葡萄糖耐受试验、肺功能测定和肺固定研究肥胖和代谢障碍对肺部结局的影响

Article DOI: 10.3791/56685-v 08:30 min March 15th, 2018
March 15th, 2018

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Summary

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肥胖的发病率在上升, 并增加了慢性肺病的风险。为了建立基本机制和预防战略, 需要有明确定义的动物模型。在这里, 我们提供三种方法 (葡萄糖耐受性测试, 身体 plethysmography 和肺固定), 以研究肥胖对肺结局的影响小鼠。

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免疫学和感染 问题 133 葡萄糖耐受性试验 肺功能 肺固定 肥胖 气道阻力 动态依从性 慢性肺部疾病
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