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Journal / Cancer Research / Radionuklid-Fluoreszenz-Reporter-Gen Imaging zu…
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Cancer Research

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JoVE Journal Cancer Research
Radionuklid-Fluoreszenz-Reporter-Gen Imaging zu Tumorprogression in Nagetier Tumormodellen verfolgen
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Radionuklid-Fluoreszenz-Reporter-Gen Imaging zu Tumorprogression in Nagetier Tumormodellen verfolgen

Article DOI: 10.3791/57088-v • 10:04 min • March 13th, 2018
March 13th, 2018 •
1, 1, 1, 1, 1, 1, 1
1Department of Imaging Chemistry and Biology, School of Biomedical Engineering and Imaging Sciences, King's College London

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Wir beschreiben ein Protokoll für die präklinische in Vivo Verfolgung von Krebsmetastasen. Es basiert auf einem Radionuklid-Fluoreszenz-Reporter Kombination von Natrium Iodid Symporter, entdeckt nichtinvasive [18F] Tetrafluoroborate-PET, und ein fluoreszierendes Protein für optimierte ex Vivo Bestätigung. Die Methode ist anwendbar für präklinische in Vivo Zelle tracking über Tumorbiologie.

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Cancer Research Ausgabe 133 Cell Tracking Reportergen imaging Natrium-Iodid-Symporter fluoreszierenden Proteins Positronen-Emissions-Tomographie [18F] Tetrafluoroborate Fluoreszenz-Mikroskopie virale gen Lieferung
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