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Whole-brain Segmentation and Change-point Analysis of Anatomical Brain MRI—Application in Premanifest Huntington’s Disease
JoVE Journal
Medicine
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JoVE Journal Medicine
Whole-brain Segmentation and Change-point Analysis of Anatomical Brain MRI—Application in Premanifest Huntington’s Disease
DOI:

09:06 min

June 09, 2018

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Chapters

  • 00:04Title
  • 01:22Atlas-based Whole Brain Segmentation
  • 05:01Change-point Analysis of Volumentric Data
  • 06:35Results: Whole-brain Segmentation and Change-point Analysis of Anatomical Brain MRI
  • 07:50Conclusion

Summary

Automatic Translation

This paper describes a statistical model for volumetric MRI data analysis, which identifies the "change-point" when brain atrophy begins in premanifest Huntington's disease. Whole-brain mapping of the change-points is achieved based on brain volumes obtained using an atlas-based segmentation pipeline of T1-weighted images.

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