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Journal / Cancer Research / En bioluminescerende og fluorescerende Orthotopic …
JoVE Journal
Cancer Research

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JoVE Journal Cancer Research
En bioluminescerende og fluorescerende Orthotopic Syngeneic Murine Model af Androgen-afhængige og kastration-resistente prostatakræft
Detecting the Ligand-binding Domain Dimerization Activity of Estrogen Receptor Alpha Using the Mammalian Two-Hybrid Assay
Journal (Cancer Research)
Detecting the Ligand-binding Domain Dimerization Activity of Estrogen Receptor Alpha Using the Mammalian Two-Hybrid Assay
Labeling of Breast Cancer Patient-derived Xenografts with Traceable Reporters for Tumor Growth and Metastasis Studies
Journal (Cancer Research)
Labeling of Breast Cancer Patient-derived Xenografts with Traceable Reporters for Tumor Growth and Metastasis Studies
 
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En bioluminescerende og fluorescerende Orthotopic Syngeneic Murine Model af Androgen-afhængige og kastration-resistente prostatakræft

Article DOI: 10.3791/57301-v • 07:25 min • March 6th, 2018
March 6th, 2018 •
1, 1, 1, *1,3, *1,2,3
1Department of Urology, Northwestern University Feinberg School of Medicine, 2The Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, 3Department of Pathology, Northwestern University Feinberg School of Medicine
* These authors contributed equally

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Målet med denne protokol er at påvise den intra-prostata injektion af prostata cancerceller, med efterfølgende kastration. Orthotopic prækliniske modeller af androgen-afhængige og kastration-resistente prostatakræft er kritisk at studere sygdomme i forbindelse med en klinisk relevant tumor mikromiljø og en immunkompetente vært.

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Kræftforskning sag 133 prostata cancer syngeneic musemodel orthotopic prostata tumor intra-prostata injektion kirurgisk kastration kirurgi androgen-afhængige prostatakræft kastration-resistente prostatakræft Urologi medicin tumor mikromiljø i vivo billeddannelse
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