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JoVE Journal Developmental Biology
Gecontroleerde corticale impact model van muis hersenletsel met therapeutische transplantatie van menselijk geïnduceerde pluripotente stamcel-afgeleide neurale cellen
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Gecontroleerde corticale impact model van muis hersenletsel met therapeutische transplantatie van menselijk geïnduceerde pluripotente stamcel-afgeleide neurale cellen

Article DOI: 10.3791/59561-v • 09:29 min • July 10th, 2019
July 10th, 2019 •
1,2, 1,2,3, 1,2,3
1Center for Neuroscience and Regenerative Medicine, Uniformed Services University, 2Department of Anatomy, Physiology, and Genetics, Uniformed Services University, 3Graduate Program in Neuroscience, Uniformed Services University

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Dit protocol demonstreert methodologieën voor een muismodel van open-schedel traumatisch hersenletsel en transplantatie van gekweekte menselijke geïnduceerde pluripotente stamcel-afgeleide cellen in de wond site. Gedrags-en histologische tests van uitkomsten van deze procedures worden ook in het kort beschreven.

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Ontwikkelingsbiologie probleem 149 traumatisch hersenletsel cortex craniectomie sensorische motor transplantatie stamcel
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