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Journal / Developmental Biology / Forbigående behandling af humane pluripotente…
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Developmental Biology

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JoVE Journal Developmental Biology
Forbigående behandling af humane pluripotente stamceller med DMSO for at fremme differentiering
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Forbigående behandling af humane pluripotente stamceller med DMSO for at fremme differentiering

Article DOI: 10.3791/59833-v • 06:55 min • July 17th, 2019
July 17th, 2019 •
1, 1, 1, 1,2
1Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 2Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine

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Generering af differentierede celletyper fra humane pluripotente stamceller (hPSCs) rummer store terapeutiske løfter, men forbliver udfordrende. Kvikskranker udviser ofte en iboende manglende evne til at skelne, selv når de stimuleres med et korrekt sæt af signaler. Beskrevet her er et simpelt værktøj til at forbedre multi differentiering på tværs af en række PSC linjer.

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Udviklingsmæssige biologi humane pluripotente stamceller differentiering DMSO Retinoblastom protein celle cyklus celle skæbne
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