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Bioink extracelular derivado da matriz de tecido sipâncreas para a impressão de construções de tecidopanpático 3D Carregadas de células

Article DOI: 10.3791/60434-v • 07:55 min • December 13th, 2019
December 13th, 2019 •
*1, *2, 2, 3, 3,4, 1,2,5
1Department of Mechanical Engineering, Pohang University of Science and Technology, 2School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, 3Asan Institute for Life Science, University of Ulsan College of Medicine and Asan Medical Center, 4Division of Hepato-Biliary and Pancreatic Surgery, Department of Surgery, University of Ulsan College of Medicine and Asan Medical Center, 5Department of Creative IT Engineering, Pohang University of Science and Technology
* These authors contributed equally

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A matriz extracelular descelularizada (dECM) pode fornecer pistas microambientais adequadas para recapitular as funções inerentes dos tecidos-alvo em uma construção projetada. Este artigo elucida os protocolos para a descelularização do tecido pancreático, avaliação do bioink dECM derivado do tecido pancreático e geração de construções de tecidopanpático 3D usando uma técnica de bioimpressão.

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Bioengenharia Edição 154 Bioink impressão de células 3D pâncreas matriz extracelular descelularizada transplante de ilhotas diabetes tipo 1
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