Journal
/
/
Osteoarthritis Pain Model Induced by Intra-Articular Injection of Mono-Iodoacetate in Rats
JoVE Journal
Medicine
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Medicine
Osteoarthritis Pain Model Induced by Intra-Articular Injection of Mono-Iodoacetate in Rats
DOI:

08:09 min

May 20, 2020

, , , , ,

Chapters

  • 00:04Introduction
  • 00:47Intra‐Articular Mono‐Iodoacetate (MIA) Injection
  • 01:48Mechanical Withdrawal Threshold (MWT)
  • 03:00Thermal Withdrawal Latency (TWL)
  • 04:17Gait Pattern Analyses
  • 05:39Results: Representative MIA Development and Characterization
  • 07:16Conclusion

Summary

Automatic Translation

This study describes the method of intra-articular injection of mono-iodoacetate in rats and discusses the resulting pain-related behaviors and histopathological changes, which provide references for future applications.

Related Videos

Read Article