Rudolf Jaenisch

Publications

• Reprogramming Factor Stoichiometry Influences the Epigenetic State and Biological Properties of Induced Pluripotent Stem Cells
  Cell Stem Cell. Dec, 2011  |   Pubmed ID: 22136932
• Surface-engineered Substrates for Improved Human Pluripotent Stem Cell Culture Under Fully Defined Conditions
  Proceedings of the National Academy of Sciences of the United States of America. Nov, 2011  |   Pubmed ID: 22065768
• Functional Integration of Dopaminergic Neurons Directly Converted from Mouse Fibroblasts
  Cell Stem Cell. Nov, 2011  |   Pubmed ID: 22019014
• Deletion of the De Novo DNA Methyltransferase Dnmt3a Promotes Lung Tumor Progression
  Proceedings of the National Academy of Sciences of the United States of America. Nov, 2011  |   Pubmed ID: 22011581
• Blimp1 Expression Predicts Embryonic Stem Cell Development In vitro
  Current Biology : CB. Oct, 2011  |   Pubmed ID: 22000107
• Transgene Excision Has No Impact on in Vivo Integration of Human IPS Derived Neural Precursors
  PloS One. 2011  |   Pubmed ID: 21961042
• Mir-290-295 Deficiency in Mice Results in Partially Penetrant Embryonic Lethality and Germ Cell Defects
  Proceedings of the National Academy of Sciences of the United States of America. Aug, 2011  |   Pubmed ID: 21844366
• Tet1 is Dispensable for Maintaining Pluripotency and Its Loss is Compatible with Embryonic and Postnatal Development
  Cell Stem Cell. Aug, 2011  |   Pubmed ID: 21816367
• Generation of Isogenic Pluripotent Stem Cells Differing Exclusively at Two Early Onset Parkinson Point Mutations
  Cell. Jul, 2011  |   Pubmed ID: 21757228
• Genetic Engineering of Human Pluripotent Cells Using TALE Nucleases
  Nature Biotechnology. Aug, 2011  |   Pubmed ID: 21738127
• De Novo DNA Methylation by Dnmt3a and Dnmt3b is Dispensable for Nuclear Reprogramming of Somatic Cells to a Pluripotent State
  Genes & Development. May, 2011  |   Pubmed ID: 21576263
• A Latent Pro-survival Function for the Mir-290-295 Cluster in Mouse Embryonic Stem Cells
  PLoS Genetics. May, 2011  |   Pubmed ID: 21573140
• Reprogramming of Postnatal Neurons into Induced Pluripotent Stem Cells by Defined Factors
  Stem Cells (Dayton, Ohio). Jun, 2011  |   Pubmed ID: 21563275
• Pan-Src Family Kinase Inhibitors Replace Sox2 During the Direct Reprogramming of Somatic Cells
  Angewandte Chemie (International Ed. in English). Jun, 2011  |   Pubmed ID: 21547985
• Genes Methylated by DNA Methyltransferase 3b Are Similar in Mouse Intestine and Human Colon Cancer
  The Journal of Clinical Investigation. May, 2011  |   Pubmed ID: 21490393
• Histone H3K27ac Separates Active from Poised Enhancers and Predicts Developmental State
  Proceedings of the National Academy of Sciences of the United States of America. Dec, 2010  |   Pubmed ID: 21106759
• Pluripotency and Cellular Reprogramming: Facts, Hypotheses, Unresolved Issues
  Cell. Nov, 2010  |   Pubmed ID: 21074044
• T-cell Receptor-driven Lymphomagenesis in Mice Derived from a Reprogrammed T Cell
  Proceedings of the National Academy of Sciences of the United States of America. Nov, 2010  |   Pubmed ID: 20956329
• Differentiated Parkinson Patient-derived Induced Pluripotent Stem Cells Grow in the Adult Rodent Brain and Reduce Motor Asymmetry in Parkinsonian Rats
  Proceedings of the National Academy of Sciences of the United States of America. Sep, 2010  |   Pubmed ID: 20798034
• Combinatorial Development of Biomaterials for Clonal Growth of Human Pluripotent Stem Cells
  Nature Materials. Sep, 2010  |   Pubmed ID: 20729850
• Position-dependent Silencing of Germline Vß Segments on TCRß Alleles Containing Preassembled VßDJßCß1 Genes
  Journal of Immunology (Baltimore, Md. : 1950). Sep, 2010  |   Pubmed ID: 20709953
• Chromatin Structure and Gene Expression Programs of Human Embryonic and Induced Pluripotent Stem Cells
  Cell Stem Cell. Aug, 2010  |   Pubmed ID: 20682450
• Reprogramming of Human Peripheral Blood Cells to Induced Pluripotent Stem Cells
  Cell Stem Cell. Jul, 2010  |   Pubmed ID: 20621045
• Musashi-2 Regulates Normal Hematopoiesis and Promotes Aggressive Myeloid Leukemia
  Nature Medicine. Aug, 2010  |   Pubmed ID: 20616797
• Functional Genomics, Proteomics, and Regulatory DNA Analysis in Isogenic Settings Using Zinc Finger Nuclease-driven Transgenesis into a Safe Harbor Locus in the Human Genome
  Genome Research. Aug, 2010  |   Pubmed ID: 20508142
• Derivation of Pre-X Inactivation Human Embryonic Stem Cells Under Physiological Oxygen Concentrations
  Cell. May, 2010  |   Pubmed ID: 20471072
• Human Embryonic Stem Cells with Biological and Epigenetic Characteristics Similar to Those of Mouse ESCs
  Proceedings of the National Academy of Sciences of the United States of America. May, 2010  |   Pubmed ID: 20442331
• Beta 2-microglobulin Deficient Mice Lack CD4-8+ Cytolytic T Cells. 1990
  Journal of Immunology (Baltimore, Md. : 1950). May, 2010  |   Pubmed ID: 20410495
• Two-step Imprinted X Inactivation: Repeat Versus Genic Silencing in the Mouse
  Molecular and Cellular Biology. Jul, 2010  |   Pubmed ID: 20404085
• Transnuclear Mice with Predefined T Cell Receptor Specificities Against Toxoplasma Gondii Obtained Via SCNT
  Science (New York, N.Y.). Apr, 2010  |   Pubmed ID: 20378817
• Generation of IPSCs from Cultured Human Malignant Cells
  Blood. May, 2010  |   Pubmed ID: 20233975
• Pluripotent Stem Cells Are Highly Susceptible Targets for Syngeneic, Allogeneic, and Xenogeneic Natural Killer Cells
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jul, 2010  |   Pubmed ID: 20145206
• TCR Beta Feedback Signals Inhibit the Coupling of Recombinationally Accessible V Beta 14 Segments with DJ Beta Complexes
  Journal of Immunology (Baltimore, Md. : 1950). Feb, 2010  |   Pubmed ID: 20042591
• Single-gene Transgenic Mouse Strains for Reprogramming Adult Somatic Cells
  Nature Methods. Jan, 2010  |   Pubmed ID: 20010831
• Technical Challenges in Using Human Induced Pluripotent Stem Cells to Model Disease
  Cell Stem Cell. Dec, 2009  |   Pubmed ID: 19951687
• Direct Cell Reprogramming is a Stochastic Process Amenable to Acceleration
  Nature. Dec, 2009  |   Pubmed ID: 19898493
• DNA Methylation Protects Hematopoietic Stem Cell Multipotency from Myeloerythroid Restriction
  Nature Genetics. Nov, 2009  |   Pubmed ID: 19801979
• Functional Characterization of Cardiomyocytes Derived from Murine Induced Pluripotent Stem Cells in Vitro
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Dec, 2009  |   Pubmed ID: 19703934
• Efficient Targeting of Expressed and Silent Genes in Human ESCs and IPSCs Using Zinc-finger Nucleases
  Nature Biotechnology. Sep, 2009  |   Pubmed ID: 19680244
• Loss of Cardiac MicroRNA-mediated Regulation Leads to Dilated Cardiomyopathy and Heart Failure
  Circulation Research. Sep, 2009  |   Pubmed ID: 19679836
• Cardiac Myocytes Derived from Murine Reprogrammed Fibroblasts: Intact Hormonal Regulation, Cardiac Ion Channel Expression and Development of Contractility
  Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2009  |   Pubmed ID: 19590195
• DNMT3B Expression Might Contribute to CpG Island Methylator Phenotype in Colorectal Cancer
  Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jun, 2009  |   Pubmed ID: 19470733
• Reprogramming of Murine Fibroblasts to Induced Pluripotent Stem Cells with Chemical Complementation of Klf4
  Proceedings of the National Academy of Sciences of the United States of America. Jun, 2009  |   Pubmed ID: 19447925
• Metastable Pluripotent States in NOD-mouse-derived ESCs
  Cell Stem Cell. Jun, 2009  |   Pubmed ID: 19427283
• HDAC2 Negatively Regulates Memory Formation and Synaptic Plasticity
  Nature. May, 2009  |   Pubmed ID: 19424149
• Epigenetic Hierarchy Governing Nestin Expression
  Stem Cells (Dayton, Ohio). May, 2009  |   Pubmed ID: 19415779
• Parkinson's Disease Patient-derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors
  Cell. Mar, 2009  |   Pubmed ID: 19269371
• Broader Implications of Defining Standards for the Pluripotency of IPSCs
  Cell Stem Cell. Mar, 2009  |   Pubmed ID: 19265657
• Phosphorylation of MeCP2 at Serine 80 Regulates Its Chromatin Association and Neurological Function
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2009  |   Pubmed ID: 19225110
• Partial Reversal of Rett Syndrome-like Symptoms in MeCP2 Mutant Mice
  Proceedings of the National Academy of Sciences of the United States of America. Feb, 2009  |   Pubmed ID: 19208815
• Chromatin Signature Reveals over a Thousand Highly Conserved Large Non-coding RNAs in Mammals
  Nature. Mar, 2009  |   Pubmed ID: 19182780
• Transgenic Mice with Defined Combinations of Drug-inducible Reprogramming Factors
  Nature Biotechnology. Feb, 2009  |   Pubmed ID: 19151700
• Microfluidic Control of Cell Pairing and Fusion
  Nature Methods. Feb, 2009  |   Pubmed ID: 19122668
• Reprogramming of Murine and Human Somatic Cells Using a Single Polycistronic Vector
  Proceedings of the National Academy of Sciences of the United States of America. Jan, 2009  |   Pubmed ID: 19109433
• Derivation and Manipulation of Murine Embryonic Stem Cells
  Methods in Molecular Biology (Clifton, N.J.). 2009  |   Pubmed ID: 19089346
• Analysis of Histone 2B-GFP Retention Reveals Slowly Cycling Hematopoietic Stem Cells
  Nature Biotechnology. Jan, 2009  |   Pubmed ID: 19060879
• Folate Deficiency Induces Genomic Uracil Misincorporation and Hypomethylation but Does Not Increase DNA Point Mutations
  Gastroenterology. Jan, 2009  |   Pubmed ID: 18992744
• Celebrating 10 Years of HESC Lines: an Interview with Rudolf Jaenisch
  Stem Cells (Dayton, Ohio). Dec, 2008  |   Pubmed ID: 19112652
• H2AZ is Enriched at Polycomb Complex Target Genes in ES Cells and is Necessary for Lineage Commitment
  Cell. Nov, 2008  |   Pubmed ID: 18992931
• A Drug-inducible System for Direct Reprogramming of Human Somatic Cells to Pluripotency
  Cell Stem Cell. Sep, 2008  |   Pubmed ID: 18786421
• Nanoparticles for Gene Transfer to Human Embryonic Stem Cell Colonies
  Nano Letters. Oct, 2008  |   Pubmed ID: 18754690
• Interview with Rudolf Jaenisch, M.D
  Rejuvenation Research. Aug, 2008  |   Pubmed ID: 18729819
• Analysis of the Mouse Embryonic Stem Cell Regulatory Networks Obtained by ChIP-chip and ChIP-PET
  Genome Biology. 2008  |   Pubmed ID: 18700969
• Connecting MicroRNA Genes to the Core Transcriptional Regulatory Circuitry of Embryonic Stem Cells
  Cell. Aug, 2008  |   Pubmed ID: 18692474
• Wnt Signaling Promotes Reprogramming of Somatic Cells to Pluripotency
  Cell Stem Cell. Aug, 2008  |   Pubmed ID: 18682236
• Reprogramming of Neural Progenitor Cells into Induced Pluripotent Stem Cells in the Absence of Exogenous Sox2 Expression
  Stem Cells (Dayton, Ohio). Oct, 2008  |   Pubmed ID: 18635867
• Folate Deficiency Induces Neurodegeneration and Brain Dysfunction in Mice Lacking Uracil DNA Glycosylase
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jul, 2008  |   Pubmed ID: 18614692
• Genome-scale DNA Methylation Maps of Pluripotent and Differentiated Cells
  Nature. Aug, 2008  |   Pubmed ID: 18600261
• A Drug-inducible Transgenic System for Direct Reprogramming of Multiple Somatic Cell Types
  Nature Biotechnology. Aug, 2008  |   Pubmed ID: 18594521
• Somatic Cell Nuclear Transfer and Derivation of Embryonic Stem Cells in the Mouse
  Methods (San Diego, Calif.). Jun, 2008  |   Pubmed ID: 18593608
• Maternal and Zygotic Dnmt1 Are Necessary and Sufficient for the Maintenance of DNA Methylation Imprints During Preimplantation Development
  Genes & Development. Jun, 2008  |   Pubmed ID: 18559477
• Dissecting Direct Reprogramming Through Integrative Genomic Analysis
  Nature. Jul, 2008  |   Pubmed ID: 18509334
• Direct Reprogramming of Terminally Differentiated Mature B Lymphocytes to Pluripotency
  Cell. Apr, 2008  |   Pubmed ID: 18423197
• Neurons Derived from Reprogrammed Fibroblasts Functionally Integrate into the Fetal Brain and Improve Symptoms of Rats with Parkinson's Disease
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2008  |   Pubmed ID: 18391196
• Promoter CpG Methylation Contributes to ES Cell Gene Regulation in Parallel with Oct4/Nanog, PcG Complex, and Histone H3 K4/K27 Trimethylation
  Cell Stem Cell. Feb, 2008  |   Pubmed ID: 18371437
• Sequential Expression of Pluripotency Markers During Direct Reprogramming of Mouse Somatic Cells
  Cell Stem Cell. Feb, 2008  |   Pubmed ID: 18371436
• C-Myc is Dispensable for Direct Reprogramming of Mouse Fibroblasts
  Cell Stem Cell. Jan, 2008  |   Pubmed ID: 18371415
• Targeted Deletion Reveals Essential and Overlapping Functions of the MiR-17 Through 92 Family of MiRNA Clusters
  Cell. Mar, 2008  |   Pubmed ID: 18329372
• Stem Cells, the Molecular Circuitry of Pluripotency and Nuclear Reprogramming
  Cell. Feb, 2008  |   Pubmed ID: 18295576
• The Pluripotency Regulator Oct4: a Role in Somatic Stem Cells?
  Cell Cycle (Georgetown, Tex.). Mar, 2008  |   Pubmed ID: 18239456
• New Advances in IPS Cell Research Do Not Obviate the Need for Human Embryonic Stem Cells
  Cell Stem Cell. Oct, 2007  |   Pubmed ID: 18371375
• Recombination Signatures Distinguish Embryonic Stem Cells Derived by Parthenogenesis and Somatic Cell Nuclear Transfer
  Cell Stem Cell. Sep, 2007  |   Pubmed ID: 18371368
• Directly Reprogrammed Fibroblasts Show Global Epigenetic Remodeling and Widespread Tissue Contribution
  Cell Stem Cell. Jun, 2007  |   Pubmed ID: 18371336
• Oct4 Expression is Not Required for Mouse Somatic Stem Cell Self-renewal
  Cell Stem Cell. Oct, 2007  |   Pubmed ID: 18159219
• Treatment of Sickle Cell Anemia Mouse Model with IPS Cells Generated from Autologous Skin
  Science (New York, N.Y.). Dec, 2007  |   Pubmed ID: 18063756
• Dnmt3b Promotes Tumorigenesis in Vivo by Gene-specific De Novo Methylation and Transcriptional Silencing
  Genes & Development. Dec, 2007  |   Pubmed ID: 18056424
• YAP1 Increases Organ Size and Expands Undifferentiated Progenitor Cells
  Current Biology : CB. Dec, 2007  |   Pubmed ID: 17980593
• DNA Methylation in the Human Cerebral Cortex is Dynamically Regulated Throughout the Life Span and Involves Differentiated Neurons
  PloS One. 2007  |   Pubmed ID: 17878930
• Direct Reprogramming of Genetically Unmodified Fibroblasts into Pluripotent Stem Cells
  Nature Biotechnology. Oct, 2007  |   Pubmed ID: 17724450
• A Chromatin Landmark and Transcription Initiation at Most Promoters in Human Cells
  Cell. Jul, 2007  |   Pubmed ID: 17632057
• Early TCR Expression and Aberrant T Cell Development in Mice with Endogenous Prerearranged T Cell Receptor Genes
  Journal of Immunology (Baltimore, Md. : 1950). Jul, 2007  |   Pubmed ID: 17617584
• Genome-wide Maps of Chromatin State in Pluripotent and Lineage-committed Cells
  Nature. Aug, 2007  |   Pubmed ID: 17603471
• In Vitro Reprogramming of Fibroblasts into a Pluripotent ES-cell-like State
  Nature. Jul, 2007  |   Pubmed ID: 17554336
• Ablation of De Novo DNA Methyltransferase Dnmt3a in the Nervous System Leads to Neuromuscular Defects and Shortened Lifespan
  Developmental Dynamics : an Official Publication of the American Association of Anatomists. Jun, 2007  |   Pubmed ID: 17477386
• Sprouty-2 Regulates Oncogenic K-ras in Lung Development and Tumorigenesis
  Genes & Development. Mar, 2007  |   Pubmed ID: 17369402
• Commentary: Isolated Stem Cells--patentable As Cultural Artifacts?
  Stem Cells (Dayton, Ohio). Jun, 2007  |   Pubmed ID: 17347494
• Expression of Oncogenic K-ras from Its Endogenous Promoter Leads to a Partial Block of Erythroid Differentiation and Hyperactivation of Cytokine-dependent Signaling Pathways
  Blood. Jun, 2007  |   Pubmed ID: 17317860
• Partial Rescue of MeCP2 Deficiency by Postnatal Activation of MeCP2
  Proceedings of the National Academy of Sciences of the United States of America. Feb, 2007  |   Pubmed ID: 17267601
• On the Cloning of Animals from Terminally Differentiated Cells
  Nature Genetics. Feb, 2007  |   Pubmed ID: 17262020
• DGCR8 is Essential for MicroRNA Biogenesis and Silencing of Embryonic Stem Cell Self-renewal
  Nature Genetics. Mar, 2007  |   Pubmed ID: 17259983
• Hematopoietic Precursor Cells Transiently Reestablish Permissiveness for X Inactivation
  Molecular and Cellular Biology. Oct, 2006  |   Pubmed ID: 16980619
• Molecular Control of Pluripotency
  Current Opinion in Genetics & Development. Oct, 2006  |   Pubmed ID: 16920351
• Mammalian Nuclear Transfer
  Developmental Dynamics : an Official Publication of the American Association of Anatomists. Sep, 2006  |   Pubmed ID: 16881069
• Nuclear Reprogramming and Pluripotency
  Nature. Jun, 2006  |   Pubmed ID: 16810240
• Reprogramming Efficiency Following Somatic Cell Nuclear Transfer is Influenced by the Differentiation and Methylation State of the Donor Nucleus
  Stem Cells (Dayton, Ohio). Sep, 2006  |   Pubmed ID: 16709876
• NT-3 Facilitates Hippocampal Plasticity and Learning and Memory by Regulating Neurogenesis
  Learning & Memory (Cold Spring Harbor, N.Y.). May-Jun, 2006  |   Pubmed ID: 16705139
• A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells
  Cell. Apr, 2006  |   Pubmed ID: 16630819
• Control of Developmental Regulators by Polycomb in Human Embryonic Stem Cells
  Cell. Apr, 2006  |   Pubmed ID: 16630818
• Polycomb Complexes Repress Developmental Regulators in Murine Embryonic Stem Cells
  Nature. May, 2006  |   Pubmed ID: 16625203
• Suppression of Intestinal Neoplasia by Deletion of Dnmt3b
  Molecular and Cellular Biology. Apr, 2006  |   Pubmed ID: 16581773
• Politically Correct Human Embryonic Stem Cells?
  The New England Journal of Medicine. Mar, 2006  |   Pubmed ID: 16540629
• The Disease Progression of Mecp2 Mutant Mice is Affected by the Level of BDNF Expression
  Neuron. Feb, 2006  |   Pubmed ID: 16446138
• ES Cells Derived from Cloned and Fertilized Blastocysts Are Transcriptionally and Functionally Indistinguishable
  Proceedings of the National Academy of Sciences of the United States of America. Jan, 2006  |   Pubmed ID: 16418286
• Severe Deficits in 5-HT2A -mediated Neurotransmission in BDNF Conditional Mutant Mice
  Journal of Neurobiology. Mar, 2006  |   Pubmed ID: 16408297
• Efficient Method to Generate Single-copy Transgenic Mice by Site-specific Integration in Embryonic Stem Cells
  Genesis (New York, N.Y. : 2000). Jan, 2006  |   Pubmed ID: 16400644
• Generation of Nuclear Transfer-derived Pluripotent ES Cells from Cloned Cdx2-deficient Blastocysts
  Nature. Jan, 2006  |   Pubmed ID: 16227971
• Postnatal Loss of Methyl-CpG Binding Protein 2 in the Forebrain is Sufficient to Mediate Behavioral Aspects of Rett Syndrome in Mice
  Biological Psychiatry. Mar, 2006  |   Pubmed ID: 16199017
• Global Loss of Imprinting Leads to Widespread Tumorigenesis in Adult Mice
  Cancer Cell. Oct, 2005  |   Pubmed ID: 16226703
• Reduced Representation Bisulfite Sequencing for Comparative High-resolution DNA Methylation Analysis
  Nucleic Acids Research. 2005  |   Pubmed ID: 16224102
• Opposing Effects of DNA Hypomethylation on Intestinal and Liver Carcinogenesis
  Proceedings of the National Academy of Sciences of the United States of America. Sep, 2005  |   Pubmed ID: 16174748
• Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells
  Cell. Sep, 2005  |   Pubmed ID: 16153702
• Reduced Cortical Activity Due to a Shift in the Balance Between Excitation and Inhibition in a Mouse Model of Rett Syndrome
  Proceedings of the National Academy of Sciences of the United States of America. Aug, 2005  |   Pubmed ID: 16116096
• Nuclear Cloning, Epigenetic Reprogramming and Cellular Differentiation
  Novartis Foundation Symposium. 2005  |   Pubmed ID: 16050253
• Characterization of a Highly Variable Eutherian MicroRNA Gene
  RNA (New York, N.Y.). Aug, 2005  |   Pubmed ID: 15987809
• Ectopic Expression of Oct-4 Blocks Progenitor-cell Differentiation and Causes Dysplasia in Epithelial Tissues
  Cell. May, 2005  |   Pubmed ID: 15882627
• Normal Eye-specific Patterning of Retinal Inputs to Murine Subcortical Visual Nuclei in the Absence of Brain-derived Neurotrophic Factor
  Visual Neuroscience. Jan-Feb, 2005  |   Pubmed ID: 15842738
• DNA CpG Hypomethylation Induces Heterochromatin Reorganization Involving the Histone Variant MacroH2A
  Journal of Cell Science. Apr, 2005  |   Pubmed ID: 15784683
• Direct in Vivo VH to JH Rearrangement Violating the 12/23 Rule
  The Journal of Experimental Medicine. Feb, 2005  |   Pubmed ID: 15699070
• X Chromosome Choice Occurs Independently of Asynchronous Replication Timing
  The Journal of Cell Biology. Jan, 2005  |   Pubmed ID: 15668296
• Human Cloning - the Science and Ethics of Nuclear Transplantation
  The New England Journal of Medicine. Dec, 2004  |   Pubmed ID: 15625328
• Developmentally Regulated Alterations in Polycomb Repressive Complex 1 Proteins on the Inactive X Chromosome
  The Journal of Cell Biology. Dec, 2004  |   Pubmed ID: 15596546
• Sixteenth Annual Pezcoller Symposium: Stem Cells and Epigenesis in Cancer
  Cancer Research. Nov, 2004  |   Pubmed ID: 15548721
• At Most Three ES Cells Contribute to the Somatic Lineages of Chimeric Mice and of Mice Produced by ES-tetraploid Complementation
  Developmental Biology. Nov, 2004  |   Pubmed ID: 15464582
• Uracil DNA Glycosylase Activity is Dispensable for Immunoglobulin Class Switch
  Science (New York, N.Y.). Aug, 2004  |   Pubmed ID: 15326357
• Nuclear Cloning of Embryonal Carcinoma Cells
  Proceedings of the National Academy of Sciences of the United States of America. Sep, 2004  |   Pubmed ID: 15306687
• Reprogramming of a Melanoma Genome by Nuclear Transplantation
  Genes & Development. Aug, 2004  |   Pubmed ID: 15289459
• Cre-lox-regulated Conditional RNA Interference from Transgenes
  Proceedings of the National Academy of Sciences of the United States of America. Jul, 2004  |   Pubmed ID: 15240889
• Increased Postischemic Brain Injury in Mice Deficient in Uracil-DNA Glycosylase
  The Journal of Clinical Investigation. Jun, 2004  |   Pubmed ID: 15199406
• Nuclear Transplantation, Embryonic Stem Cells and the Potential for Cell Therapy
  The Hematology Journal : the Official Journal of the European Haematology Association / EHA. 2004  |   Pubmed ID: 15190291
• Expression of MeCP2 in Postmitotic Neurons Rescues Rett Syndrome in Mice
  Proceedings of the National Academy of Sciences of the United States of America. Apr, 2004  |   Pubmed ID: 15069197
• Wt1 Functions in the Development of Germ Cells in Addition to Somatic Cell Lineages of the Testis
  Developmental Biology. Apr, 2004  |   Pubmed ID: 15063178
• Mice Cloned from Olfactory Sensory Neurons
  Nature. Mar, 2004  |   Pubmed ID: 14990966
• Micromanipulating Dosage Compensation: Understanding X-chromosome Inactivation Through Nuclear Transplantation
  Seminars in Cell & Developmental Biology. Dec, 2003  |   Pubmed ID: 15015742
• Differentiation of F1 Embryonic Stem Cells into Viable Male and Female Mice by Tetraploid Embryo Complementation
  Methods in Enzymology. 2003  |   Pubmed ID: 14696335
• Derepression of BDNF Transcription Involves Calcium-dependent Phosphorylation of MeCP2
  Science (New York, N.Y.). Oct, 2003  |   Pubmed ID: 14593183
• Nuclear Transplantation, Embryonic Stem Cells, and the Potential for Cell Therapy
  The New England Journal of Medicine. Jul, 2003  |   Pubmed ID: 12867612
• Hybrid Embryonic Stem Cell-derived Tetraploid Mice Show Apparently Normal Morphological, Physiological, and Neurological Characteristics
  Molecular and Cellular Biology. Jun, 2003  |   Pubmed ID: 12748299
• Stem Cells. Setting Standards for Human Embryonic Stem Cells
  Science (New York, N.Y.). May, 2003  |   Pubmed ID: 12738841
• Induction of Tumors in Mice by Genomic Hypomethylation
  Science (New York, N.Y.). Apr, 2003  |   Pubmed ID: 12702876
• Chromosomal Instability and Tumors Promoted by DNA Hypomethylation
  Science (New York, N.Y.). Apr, 2003  |   Pubmed ID: 12702868
• Asynchronous Replication Timing of Imprinted Loci is Independent of DNA Methylation, but Consistent with Differential Subnuclear Localization
  Genes & Development. Mar, 2003  |   Pubmed ID: 12651894
• HIF-1alpha is Essential for Myeloid Cell-mediated Inflammation
  Cell. Mar, 2003  |   Pubmed ID: 12628185
• Incomplete Reactivation of Oct4-related Genes in Mouse Embryos Cloned from Somatic Nuclei
  Development (Cambridge, England). Apr, 2003  |   Pubmed ID: 12620990
• Epigenetic Regulation of Gene Expression: How the Genome Integrates Intrinsic and Environmental Signals
  Nature Genetics. Mar, 2003  |   Pubmed ID: 12610534
• Rapid Generation of Inducible Mouse Mutants
  Nucleic Acids Research. Feb, 2003  |   Pubmed ID: 12582257
• Stroke Damage in Mice After Knocking the Neutrophin-4 Gene into the Brain-derived Neurotrophic Factor Locus
  Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Feb, 2003  |   Pubmed ID: 12571446
• Nuclear Cloning, Embryonic Stem Cells, and Transplantation Therapy
  Harvey Lectures. -2003, 2002  |   Pubmed ID: 16033160
• Nuclear Transplantation: Lessons from Frogs and Mice
  Current Opinion in Cell Biology. Dec, 2002  |   Pubmed ID: 12473349
• X-chromosome Inactivation During Spermatogenesis is Regulated by an Xist/Tsix-independent Mechanism in the Mouse
  Genesis (New York, N.Y. : 2000). Dec, 2002  |   Pubmed ID: 12434336
• Transcriptional Profiling of a Mouse Model for Rett Syndrome Reveals Subtle Transcriptional Changes in the Brain
  Proceedings of the National Academy of Sciences of the United States of America. Nov, 2002  |   Pubmed ID: 12432090
• Meiotic Sex Chromosome Inactivation in Male Mice with Targeted Disruptions of Xist
  Journal of Cell Science. Nov, 2002  |   Pubmed ID: 12356914
• Abnormal Gene Expression in Cloned Mice Derived from Embryonic Stem Cell and Cumulus Cell Nuclei
  Proceedings of the National Academy of Sciences of the United States of America. Oct, 2002  |   Pubmed ID: 12235366
• Brain-derived Neurotrophic Factor is Essential for Opiate-induced Plasticity of Noradrenergic Neurons
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2002  |   Pubmed ID: 12019333
• Male and Female Mice Derived from the Same Embryonic Stem Cell Clone by Tetraploid Embryo Complementation
  Nature Biotechnology. May, 2002  |   Pubmed ID: 11981557
• Correction of a Genetic Defect by Nuclear Transplantation and Combined Cell and Gene Therapy
  Cell. Apr, 2002  |   Pubmed ID: 11955443
• Dnmt1 Overexpression Causes Genomic Hypermethylation, Loss of Imprinting, and Embryonic Lethality
  Molecular and Cellular Biology. Apr, 2002  |   Pubmed ID: 11884600
• Monoclonal Mice Generated by Nuclear Transfer from Mature B and T Donor Cells
  Nature. Feb, 2002  |   Pubmed ID: 11875572
• Flp Recombinase Regulated LacZ Expression at the ROSA26 Locus
  Genesis (New York, N.Y. : 2000). Feb, 2002  |   Pubmed ID: 11857816
• Neurotrophin-3 Promotes Cell Death Induced in Cerebral Ischemia, Oxygen-glucose Deprivation, and Oxidative Stress: Possible Involvement of Oxygen Free Radicals
  Neurobiology of Disease. Feb, 2002  |   Pubmed ID: 11848682
• Chromosomal Silencing and Localization Are Mediated by Different Domains of Xist RNA
  Nature Genetics. Feb, 2002  |   Pubmed ID: 11780141