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JoVE Journal
Immunology and Infection

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Zebrafish as a Model to Assess the Teratogenic Potential of Nitrite
 

Zebrafish as a Model to Assess the Teratogenic Potential of Nitrite

Article DOI: 10.3791/53615-v 07:29 min February 16th, 2016
February 16th, 2016

章节

总结概括

Exposure to teratogens may cause birth defects. Zebrafish are useful for determining the teratogenic potential of chemicals. We demonstrate the utility of zebrafish by exposing embryos to various levels of nitrite and also at different times of exposure. We show that nitrite can be toxic and cause severe developmental defects.

Tags

Zebrafish Nitrite Teratogenic Potential Developmental Toxicology Embryonic Development Zebrafish Embryo Microscope Wild-type Zebrafish Strains Tuebingen Strain Fish Water Mating Tanks Eggs Tea Strainer Embryos E3 Buffer
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