Waiting
登录处理中...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Cancer Research / Modeling Oral-Esophageal Squamous Cell Carcinoma…
JoVE Journal
Cancer Research

需要订阅 JoVE 才能查看此 内容. 登录或开始免费试用。

JoVE Journal Cancer Research
Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids
How to Study Basement Membrane Stiffness as a Biophysical Trigger in Prostate Cancer and Other Age-related Pathologies or Metabolic Diseases
Journal (Cancer Research)
How to Study Basement Membrane Stiffness as a Biophysical Trigger in Prostate Cancer and Other Age-related Pathologies or Metabolic Diseases
Analyzing Bone Marrow Microenvironment in Murine Hematological Malignancies (Video) | JoVE
Journal (Cancer Research)
Analyzing Bone Marrow Microenvironment in Murine Hematological Malignancies (Video) | JoVE
 

Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids

Article DOI: 10.3791/64676-v • 10:43 min • December 23rd, 2022
December 23rd, 2022 •
*1, *1,2, 1, 1, 1, 1, 1, 1,3, 1,3, 4, 1,2, 1,5, 1,6, 1,7, 1,5, 1,2,5
1Herbert Irving Comprehensive Cancer Center, Columbia University, 2Organoid and Cell Culture Core, Columbia University Digestive and Liver Diseases Research Center, Columbia University, 3Department of Otolaryngology, Head and Neck Surgery, Columbia University, 4Histopathology Facility, Fox Chase Cancer Center, 5Division of Digestive and Liver Diseases, Department of Medicine, Columbia University, 6Department of Genetics and Development, Columbia University, 7Section of Oral, Diagnostic and Rehabilitation Sciences, College of Dental Medicine, Columbia University
* These authors contributed equally

章节

总结概括
Automatic Translation

This protocol describes the key steps to generate and characterize murine oral-esophageal 3D organoids that represent normal, preneoplastic, and squamous cell carcinoma lesions induced via chemical carcinogenesis.

Tags

Modeling Oral-esophageal Squamous Cell Carcinoma 3D Organoids ESCC Molecular Changes Genetic Heterogeneity Mutagen-induced Tumors Therapeutic Strategies Genetic Changes Tumorigenesis Animal Dissection Organ Collection Skin Incision Cervical Trachea Thoracic Trachea Peritoneum
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter