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Journal / Cancer Research / 肿瘤移植用于评估小鼠肿瘤浸润CD8 +…
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Cancer Research

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肿瘤移植用于评估小鼠肿瘤浸润CD8 + T细胞的动力学
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肿瘤移植用于评估小鼠肿瘤浸润CD8 + T细胞的动力学

Article DOI: 10.3791/62442-v • 07:36 min • June 12th, 2021
June 12th, 2021 •
1, 1, 2, 1, 2, 1, 3, 1, 1, 1, 1, 1, 1, 1, 1, 4, 1, 5, 1
1Institute of Immunology, Third Military Medical University, 2Guanghua School of Stomatology, Guangdong Provincial Key Laboratory of Stomatology, Stomatological Hospital, Sun Yat-Sen University, 3Shigatse Branch, Xinqiao Hospital, Third Military Medical University, 4Department of Emergency Medicine, Southwest Hospital, Third Military Medical University, 5Cancer Center, The General Hospital of Western Theater Command

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Summary
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在这里，我们提出了一种肿瘤移植方案，用于表征小鼠肿瘤模型中肿瘤固有和外周来源的肿瘤浸润淋巴细胞。通过流式细胞术特异性追踪受体来源的免疫细胞的流入，揭示了抗肿瘤免疫反应期间这些细胞表型和功能变化的动力学。

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癌症研究，第172期，
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