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Journal / Medicine / 超高分辨率小鼠光学相干层析成像辅助眼内注射在视网膜基因治疗中的应用…
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超高分辨率小鼠光学相干层析成像辅助眼内注射在视网膜基因治疗中的应用

Article DOI: 10.3791/55894-v • 10:10 min • November 2nd, 2018
November 2nd, 2018 •
1,2, 1,2,3,4,5,6,7
1Research Service, VA Western New York Healthcare System, 2Department of Ophthalmology, (Ross Eye Institute), Jacobs School of Medicine and Biomedical Sciences, University at Buffalo- SUNY, 3Pharmacology/Toxicology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo- SUNY, 4Physiology/Biophysics, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo- SUNY, 5Neuroscience Program, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo- SUNY, 6The RNA Institute, University at Buffalo- SUNY, 7The SUNY Eye Institute

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在这里, 我们展示了一种新的方法, 使用高分辨率光谱域光学相干断层扫描 (hr-sd-oct), 以协助将基因治疗剂传递到视网膜下空间, 评估其区域覆盖, 并表征光感受器的活力。

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医学 第141期 光学相干层析成像 视网膜退化 gre足够立体显微镜 成像 眼内注射 活体 显微镜 光感受器 临床前 实时 视网膜 视网膜亚视网膜。
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