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Journal / Developmental Biology / Evaluatie van schade-geïnduceerde senescentie en…
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Developmental Biology

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JoVE Journal Developmental Biology
Evaluatie van schade-geïnduceerde senescentie en In Vivo herprogrammering in de skeletspieren
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Evaluatie van schade-geïnduceerde senescentie en In Vivo herprogrammering in de skeletspieren

Article DOI: 10.3791/56201-v • 09:14 min • October 26th, 2017
October 26th, 2017 •
1, 1, 1
1Cellular Plasticity & Disease Modelling, Department of Developmental & Stem Cell Biology, CNRS UMR 3738, Institut Pasteur

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Hier presenteren we een gedetailleerd protocol bij het detecteren van zowel verouderend en pluripotente stamcellen in de skeletspieren op letsel tijdens het inducerende in vivo herprogrammering. Deze methode is geschikt voor de evaluatie van de rol van cellulaire senescentie tijdens Weefselregeneratie en herprogrammering in vivo.

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Ontwikkelingsbiologie kwestie 128 cellulaire senescentie in vivo herprogrammering pluripotente stamcellen Herprogrammeerbare muismodel spier letsel cardiotoxin regeneratie senescentie-geassocieerde β-galactosidase kleuring
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