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Modellering af hjernemetastase ved intern halspulsåreinjektion af kræftceller

Article DOI: 10.3791/64216-v • 10:01 min • August 2nd, 2022
August 2nd, 2022 •
1, 2, 1, 3, 2, *1,4, *1,5
1UQ Centre for Clinical Research, The University of Queensland, 2Centre for Advanced Imaging, Australian Institute for Bioengineering and Nanotechnology and ARC Training Centre for Innovation in Biomedical Imaging Technology, The University of Queensland, 3School of Biomedical Sciences, The University of Queensland, 4Mater Research and Mater Research Institute, The University of Queensland, 5Pathology Queensland, Royal Brisbane Women's Hospital
* These authors contributed equally

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Hjernemetastase er en årsag til alvorlig sygelighed og dødelighed hos kræftpatienter. De fleste hjernemetastase musemodeller kompliceres af systemiske metastaser, der forvirrer analyse af dødelighed og terapeutiske interventionsresultater. Præsenteret her er en protokol for intern carotisinjektion af kræftceller, der producerer konsistente intrakranielle tumorer med minimale systemiske tumorer.

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Kræftforskning nummer 186
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