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Immunology and Infection

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JoVE Journal Immunology and Infection
Utvikling av en hepatitt B virus Reporter system for å overvåke tidlige stadier av Replication Cycle
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Utvikling av en hepatitt B virus Reporter system for å overvåke tidlige stadier av Replication Cycle

Article DOI: 10.3791/54849-v • 09:35 min • February 1st, 2017
February 1st, 2017 •
1, 1, 1, 2, 1, 1
1Research Center for Hepatitis and Immunology, National Center for Global Health and Medicine, 2Central Pharmaceutical Research Institute, Japan Tobacco Inc.

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Her beskriver vi en nyutviklet hepatitt B-virus (HBV) reporter system for å overvåke de tidlige stadier av HBV-livssyklusen. Denne forenklede in vitro-system skal hjelpe til screening av anti-HBV-midler ved hjelp av en high-throughput-strategi.

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Infeksjon hepatitt B-virus viral vektor kovalent lukket sirkulært DNA hepatocytter replikasjonssyklus NTCP
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